Fund Universe

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☆GREAT POINT PARTNERS LLC

CIK 0001281446 · holdings for 2026Q2 (change vs 2026Q1) · in signal universe
Quality Q
0.066
AUM ($M)
424
Positions
37
Turnover
0.41
Top-10 wt
54%
Herfindahl
0.040
History (qtrs)
6
Excess Return
+1.1%

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Quarter
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Security type

Holdings · 50 positions · portfolio value $424M

TickerNameActivitySecurity Type WeightΔ Weight Value ($M)SharesΔ Shares Qtrs HeldExcess Return
☆VOR funds › VOR BIOPHARMA INC TRIM — 7.4% -0.3% 31.3 1,700,000 -50,000 3 +183.8%
☆ABVX funds › ABIVAX SA NEW — 6.4% +6.4% 27.2 204,314 +204,314 1 -3.0% re-entry
☆VERA funds › VERA THERAPEUTICS INC ADD — 6.1% +4.1% 25.8 600,836 +401,488 2 -77.9%
☆ZURA funds › ZURA BIO LTD HOLD — 5.9% -0.3% 24.9 4,215,930 +0 5 —
☆ALMS funds › ALUMIS INC HOLD — 5.7% +1.1% 24.1 856,061 +0 2 -41.1%
☆SLGL funds › SOL-GEL TECHNOLOGIES LTD HOLD — 4.8% -0.5% 20.3 274,363 +0 2 +1.1%
☆DFTX funds › DEFINIUM THERAPEUTICS INC NEW — 4.7% +4.7% 20.0 425,000 +425,000 1 +1972.2%
☆ANNX funds › ANNEXON INC ADD — 4.7% +1.3% 20.0 3,500,000 +1,000,000 2 -21.1%
☆ORKA funds › ORUKA THERAPEUTICS INC HOLD — 4.1% +1.9% 17.4 183,330 +0 4 +605.3%
☆MLTX funds › MOONLAKE IMMUNOTHERAPEUTICS ADD — 3.9% +1.6% 16.7 855,813 +355,813 2 -43.5%
☆SGMT funds › SAGIMET BIOSCIENCES INC NEW — 3.7% +3.7% 15.7 2,029,933 +2,029,933 1 +550.6%
☆CTNM funds › CONTINEUM THERAPEUTICS INC ADD — 3.6% +1.0% 15.1 921,481 +121,283 3 +14.1%
☆IMMX funds › IMMIX BIOPHARMA INC ADD — 3.1% +2.3% 13.2 1,277,642 +927,642 2 +53.8%
☆CLYM funds › CLIMB BIO INC TRIM — 3.1% +0.8% 13.0 1,000,000 -334,130 3 +1737.7%
☆AMLX funds › AMYLYX PHARMACEUTICALS INC TRIM — 3.0% -3.0% 12.6 700,000 -1,050,000 5 —
☆NKTR funds › NEKTAR THERAPEUTICS TRIM — 2.9% -2.7% 12.2 175,000 -141,453 4 +146.7%
☆NGNE funds › NEUROGENE INC TRIM — 2.6% +0.1% 11.1 352,180 -147,820 5 —
☆LBRX funds › LB PHARMACEUTICALS INC ADD — 2.4% +0.6% 10.3 317,221 +17,221 2 +275.0%
☆IRD funds › OPUS GENETICS INC ADD — 1.9% +1.5% 8.1 1,970,187 +1,645,847 2 -45.8%
☆EPRX funds › EUPRAXIA PHARMACEUTICALS INC HOLD — 1.9% -0.3% 7.9 1,200,000 +0 4 +4.3%
☆DRUG funds › BRIGHT MINDS BIOSCIENCES INC TRIM — 1.8% -2.1% 7.7 109,603 -110,397 2 -49.0%
☆IFRX funds › INFLARX NV NEW — 1.6% +1.6% 6.8 3,046,557 +3,046,557 1 -81.3%
☆RLMD funds › RELMADA THERAPEUTICS INC HOLD — 1.4% -0.1% 5.8 842,106 +0 2 +44.9%
☆JATT funds › JATT II ACQUISITION CORP NEW — 1.3% +1.3% 5.7 500,000 +500,000 1 +49.0%
☆CGEM funds › CULLINAN THERAPEUTICS INC HOLD — 1.3% +0.2% 5.5 300,000 +0 3 +187.6%
☆ALT funds › ALTIMMUNE INC NEW — 1.2% +1.2% 5.3 1,741,232 +1,741,232 1 -1.8%
☆AMAN funds › AMANAT ACQUISITION CORP NEW — 1.2% +1.2% 5.1 500,000 +500,000 1 -2.8%
☆RZLT funds › REZOLUTE INC HOLD — 1.2% +0.5% 4.9 951,809 +0 5 —
☆SLN funds › SILENCE THERAPEUTICS PLC TRIM — 1.2% -0.2% 4.9 450,000 -570,489 3 +139.2%
☆PALI funds › PALISADE BIO INC TRIM — 1.1% -0.3% 4.8 2,284,819 -1,120,938 2 +28.8%
☆EVMN funds › EVOMMUNE INC HOLD — 1.0% -0.8% 4.3 325,000 +0 3 -56.4%
☆SCYX funds › SCYNEXIS INC NEW — 0.9% +0.9% 3.8 944,292 +944,292 1 -45.1%
☆ELVN funds › ENLIVEN THERAPEUTICS INC NEW — 0.8% +0.8% 3.6 70,000 +70,000 1 +390.8%
☆HUMA funds › HUMACYTE INC HOLD — 0.7% +0.1% 2.9 3,750,000 +0 2 -104.3%
☆RNTX funds › REIN THERAPEUTICS INC NEW — 0.6% +0.6% 2.7 2,575,000 +2,575,000 1 -89.5%
☆DBVT funds › DBV TECHNOLOGIES S A NEW — 0.6% +0.6% 2.6 156,906 +156,906 1 -94.3% re-entry
☆PMN funds › PROMIS NEUROSCIENCES INC TRIM — 0.3% -0.9% 1.1 86,150 -285,252 2 -47.5%
☆CUSIP:811292200 funds › SCYNEXIS INC EXIT — 0.0% -1.7% 0.0 0 -7,554,347 0 —
☆CNTX funds › CONTEXT THERAPEUTICS INC EXIT — 0.0% -1.4% 0.0 0 -2,238,496 0 —
☆IMVT funds › IMMUNOVANT INC EXIT — 0.0% -3.3% 0.0 0 -545,625 0 —
☆TENX funds › TENAX THERAPEUTICS INC EXIT — 0.0% -1.3% 0.0 0 -327,307 0 -64.2%
☆APGE funds › APOGEE THERAPEUTICS INC EXIT — 0.0% -7.7% 0.0 0 -374,000 0 —
☆UNCY funds › UNICYCIVE THERAPEUTICS INC EXIT — 0.0% -1.3% 0.0 0 -796,558 0 —
☆CUSIP:483497103 funds › KALVISTA PHARMACEUTICALS INC EXIT — 0.0% -3.3% 0.0 0 -675,000 0 —
☆CMPX funds › COMPASS THERAPEUTICS INC EXIT — 0.0% -1.7% 0.0 0 -1,350,000 0 -138.5%
☆AVTX funds › AVALO THERAPEUTICS INC EXIT — 0.0% -0.5% 0.0 0 -124,666 0 -33.0%
☆ZBIO funds › ZENAS BIOPHARMA INC EXIT — 0.0% -2.5% 0.0 0 -524,066 0 -123.6%
☆PHVS funds › PHARVARIS N V EXIT — 0.0% -0.6% 0.0 0 -82,800 0 +19.0%
☆JBIO funds › JADE BIOSCIENCES INC EXIT — 0.0% -3.3% 0.0 0 -964,462 0 —
☆ALKS funds › ALKERMES PLC EXIT — 0.0% -0.4% 0.0 0 -50,000 0 +25.4%

Point-in-time history

Each row is this fund as of that period, not as of today — what the scoring for that quarter actually saw.
PeriodAUM ($M)Positions TurnoverTop-10 wtHerfindahl Quality Q Skill Universe
2026Q2 424 37 0.41 54% 0.040 0.067 — in
2026Q1 408 39 0.43 54% 0.040 0.062 — in
2025Q4 308 29 0.48 62% 0.049 0.037 — in
2025Q3 240 28 0.45 64% 0.053 0.044 — in
2025Q2 154 26 0.49 67% 0.060 0.031 — entered
2025Q1 184 31 0.00 55% 0.043 0.000 — out
Long US-equity 13F disclosures only · up to 45-day reporting lag · sells = reduce/avoid, not short. JSON: /api/signals · /api/funds · /api/status